[Chronic autoimmune urticaria as a possible non endocrine manifestation of autoimmune polyglandular syndrome type II].

The autoimmune polyglandular syndromes are infrequent Alpha-trypsin and complement factors C3 and C4, as well as factor B, were normal. Serological testing for HBV, HCV and HIV proved negative. With the suspicion of autoimmune chronic urticaria (ACU), autologous serum testing was carried out and proved positive, thereby confirming the disease. Following the failure of other treatments with oral antihistamines and corticosteroids, cyclosporine was started, followed by control of the urticaria. Coinciding with the development of urticaria, the patient showed an increase in antithyroid antibodies (anti-TPO: 139.1 IU/ml; anti-TG: 409.7 IU/ml; TRAb: 3.75 IU/l), with a posterior decrease in their respective titers -though this was not associated with improvement of the skin lesions. At the time of writing the patient is receiving immunosupnloaded from http://www.elsevier.es, day 16/03/2018. This copy is for personal use. Any transmission of this document by any media or format is strictly prohibited.